IRF9 antibody
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935106861
info@markelab.com
name
IRF9 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04397
tested applications
ELISA, WB, IHC, IF, IP
Description
Transcription factor that mediates signaling by type I IFNs(IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases(TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element(ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | interferon regulatory factor 9 (IRF9) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 48kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q00978 |
| Gene ID | 10379 |
| Alias | Interferon regulatory factor 9 (IRF-9),IFN-alpha-responsive transcription factor subunit,ISGF3 p48 subunit,Interferon-stimulated gene factor 3 gamma (ISGF-3 gamma),Transcriptional regulator ISGF3 subunit gamma,IRF9,ISGF3G |
| Background | Antibody anti-IRF9 |
| Status | RUO |
| Note | Mol. Weight 48 kDa |
Descripción
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