IRF6 antibody

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935106861
info@markelab.com
name
IRF6 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04393
tested applications
ELISA, WB

Description

Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development(By similarity). Plays a role in regulating mammary epithelial cell proliferation(By similarity). May regulate WDR65 transcription(By similarity).

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
interferon regulatory factor 6 (IRF6)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
55-65 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
O14896
Gene ID
3664
Alias
Interferon regulatory factor 6 (IRF-6),IRF6
Background
Antibody anti-IRF6
Status
RUO
Note
Mol. Weight 55-65 kDa

Descripción

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Interferon Regulatory Factor 6 (IRF6) Antibody

IRF6 Antibody is a Rabbit Polyclonal antibody against IRF6. This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.

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