IRAK3 antibody

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Description
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
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Product specifications
| Category | Primary Antibodies | 
| Immunogen Target | IRAK3 (IRAK3) | 
| Host | Rabbit | 
| Reactivity | Human | 
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 | 
| Clonality | polyclonal | 
| Conjugation | Unconjugated | 
| Isotype | IgG | 
| Observed MW | 68kDa | 
| Purity | ≥95% as determined by SDS-PAGE | 
| Purification | Immunogen affinity purified | 
| Size 1 | 100µg | 
| Form | liquid | 
| Tested Applications | ELISA, WB, IHC | 
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) | 
| UniProt ID | Q9Y616 | 
| Gene ID | 11213 | 
| Alias | Interleukin-1 receptor-associated kinase 3 (IRAK-3),IL-1 receptor-associated kinase M (IRAK-M),Inactive IL-1 receptor-associated kinase 3,IRAK3 | 
| Background | Antibody anti-IRAK3 | 
| Status | RUO | 
| Note | Mol. Weight 68 kDa | 
Descripción
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IRAK3 antibody
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
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IRAK3 antibody
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
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