ITGA6 antibody
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Description
ITGA6, also named as CD49f and VLA-6, belongs to the integrin alpha chain family. It is a receptor for laminin on platelets. ITGA6 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Defects in ITGA6 are a cause of epidermolysis bullosa letalis with pyloric atresia(EB-PA) which also known as junctional epidermolysis bullosa with pyloric atresia(PA-JEB) or aplasia cutis congenita with gastrointestinal atresia.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | integrin, alpha 6 (ITGA6) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 120 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P23229 |
| Gene ID | 3655 |
| Alias | JEB6,CD49f,VLA-6,ITGA6A,ITGA6B,Integrin alpha-6,CD49 antigen-like family member F |
| Background | Antibody anti-ITGA6 |
| Status | RUO |
| Note | Mol. Weight 120 kDa |
Descripción
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ITGA6, also named as CD49f and VLA-6, belongs to the integrin alpha chain family. It is a receptor for laminin on platelets. ITGA6 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Defects in ITGA6 are a cause of epidermolysis bullosa letalis with pyloric atresia(EB-PA) which also known as junctional epidermolysis bullosa with pyloric atresia(PA-JEB) or aplasia cutis congenita with gastrointestinal atresia.
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