IL32 antibody
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Name
IL32 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab04270
Tested Applications
ELISA, IHC, WB
Description
Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK.
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | interleukin 32 (IL32) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 27kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P24001 |
| Gene ID | 9235 |
| Alias | NK4,TAIF,TAIFa,TAIFb,TAIFc,TAIFd,IL-32beta,IL-32alpha,IL-32delta,IL-32gamma,Natural killer cells protein 4,Tumor necrosis factor alpha-inducing factor |
| Background | Antibody anti-IL32 |
| Status | RUO |
| Note | Mol. Weight 27 kDa |
Background
Interleukin 32 (IL32) is a relatively newly discovered pro-inflammatory cytokine, originally identified in 2005. It is unique because it does not belong to the classical cytokine families, such as the IL-6 or IL-1 families, and its function is primarily associated with the regulation of inflammation. IL-32 is produced by a variety of cell types, including T cells, natural killer (NK) cells, monocytes, macrophages, fibroblasts, epithelial cells, and endothelial cells, underscoring its broad role in immune regulation. IL-32 expression is induced by other cytokines such as IFN-γ (interferon-gamma), IL-12, IL-18, and TNF-α. Its expression is also elevated in response to pathogen-associated molecular patterns (PAMPs) such as lipopolysaccharides (LPS) found on bacterial surfaces, signifying its role in innate immune responses to infection.
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