IL22RA1 antibody
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Description
Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | interleukin 22 receptor, alpha 1 (IL22RA1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 62 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8N6P7 |
| Gene ID | 58985 |
| Alias | Interleukin-22 receptor subunit alpha-1 (IL-22 receptor subunit alpha-1, IL-22R-alpha-1, IL-22RA1),Cytokine receptor class-II member 9,Cytokine receptor family 2 member 9 (CRF2-9),ZcytoR11,IL22RA1,IL22R |
| Background | Antibody anti-IL22RA1 |
| Status | RUO |
| Note | Mol. Weight 62 kDa |
Descripción
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