anti- IL1R2 antibody

Descripción

Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2(membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

Características del producto

clonality

polyclonal

reactivity

human

immunogen target

interleukin 1 receptor, type II

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB

observerd MW

45 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500-1:2000

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

IL1R2

alias

IL1R2,CD121d. IL1 RII

uniprot id

https://www.uniprot.org/uniprotkb/P27930

gene id

https://www.ncbi.nlm.nih.gov/gene/7850

note

This product is for research use only.

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Human IL1R2(Interleukin 1 Receptor Type II) ELISA Kit

proveedor

FineTest

reference

EH0187

reactivity

human

status

RUO

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