NFKBIB antibody

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935106861
info@markelab.com
name
NFKBIB antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04199
tested applications
ELISA, WB, IHC, IF
Description
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta (NFKBIB) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 40 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, IF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q15653 |
Gene ID | 4793 |
Alias | NF-kappa-B inhibitor beta (NF-kappa-BIB),I-kappa-B-beta (IkB-B, IkB-beta, IkappaBbeta),Thyroid receptor-interacting protein 9 (TR-interacting protein 9, TRIP-9),NFKBIB,IKBB,TRIP9 |
Background | Antibody anti-NFKBIB |
Status | RUO |
Note | Mol. Weight 40 kDa |
Descripción
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NFKBIB antibody
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
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