NFKBIA antibody
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935106861
info@markelab.com
name
NFKBIA antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04198
tested applications
ELISA, WB, IHC, IF
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 39 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P25963 |
| Gene ID | 4792 |
| Alias | NF-kappa-B inhibitor alpha,I-kappa-B-alpha (IkB-alpha, IkappaBalpha),Major histocompatibility complex enhancer-binding protein MAD3,NFKBIA,IKBA,MAD3,NFKBI |
| Background | Antibody anti-NFKBIA |
| Status | RUO |
| Note | Mol. Weight 39 kDa |
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This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
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