NFKBIA antibody

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935106861
info@markelab.com
name
NFKBIA antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04196
tested applications
ELISA, IHC, IF, WB, IP, FC

Description

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA)
Host
Rabbit
Reactivity
Human, Mouse, Rat, Pig
Recommended Dilution
WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
39 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, IHC, IF, WB, IP, FC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P25963
Gene ID
4792
Alias
NF-kappa-B inhibitor alpha,I-kappa-B-alpha (IkB-alpha, IkappaBalpha),Major histocompatibility complex enhancer-binding protein MAD3,NFKBIA,IKBA,MAD3,NFKBI
Background
Antibody anti-NFKBIA
Status
RUO
Note
Mol. Weight 39 kDa

Descripción

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FNab04196

NFKBIA antibody

This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Ver Producto