IFT57 antibody
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935106861
info@markelab.com
name
IFT57 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04160
tested applications
ELISA, WB, IHC, IP
Description
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway(By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8(CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | intraflagellar transport 57 homolog(Chlamydomonas) (IFT57) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 49kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9NWB7 |
| Gene ID | 55081 |
| Alias | Intraflagellar transport protein 57 homolog,Dermal papilla-derived protein 8,Estrogen-related receptor beta-like protein 1,HIP1-interacting protein,MHS4R2,IFT57,DERP8,ESRRBL1,HIPPI |
| Background | Antibody anti-IFT57 |
| Status | RUO |
| Note | Mol. Weight 49 kDa |
Descripción
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