IFIT5 antibody

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935106861
info@markelab.com
name
IFIT5 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04139
tested applications
ELISA, WB, IHC

Description

Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group(PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
interferon-induced protein with tetratricopeptide repeats 5 (IFIT5)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
56-58 kDa, 48 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q13325
Gene ID
24138
Alias
Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5),Interferon-induced 58 kDa protein,Retinoic acid- and interferon-inducible 58 kDa protein (P58),IFIT5,ISG58,RI58
Background
Antibody anti-IFIT5
Status
RUO
Note
Mol. Weight 56-58 kDa, 48 kDa

Descripción

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