IFIT5 antibody

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935106861
info@markelab.com
name
IFIT5 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04139
tested applications
ELISA, WB, IHC
Description
Interferon-induced RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group(PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Also recognizes and binds tRNAs.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | interferon-induced protein with tetratricopeptide repeats 5 (IFIT5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 56-58 kDa, 48 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q13325 |
| Gene ID | 24138 |
| Alias | Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5),Interferon-induced 58 kDa protein,Retinoic acid- and interferon-inducible 58 kDa protein (P58),IFIT5,ISG58,RI58 |
| Background | Antibody anti-IFIT5 |
| Status | RUO |
| Note | Mol. Weight 56-58 kDa, 48 kDa |
Descripción
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