HSPB8 antibody
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Description
Displays temperature-dependent chaperone activity.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | heat shock 22kDa protein 8 (HSPB8) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 20-22 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9UJY1 |
| Gene ID | 26353 |
| Alias | Heat shock protein beta-8 (HspB8),Alpha-crystallin C chain,E2-induced gene 1 protein,Protein kinase H11,Small stress protein-like protein HSP22,HSPB8,CRYAC,E2IG1,HSP22 |
| Background | Antibody anti-HSPB8 |
| Status | RUO |
| Note | Mol. Weight 20-22 kDa |
Descripción
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Recombinant Human HSPB8
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Heat Shock Protein Beta 8 (HSPB8) Antibody
HSPB8 Antibody is a Rabbit Polyclonal antibody against HSPB8. The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
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