HSPA1L antibody

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935106861
info@markelab.com
name
HSPA1L antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04055
tested applications
ELISA, IHC, IF, WB

Description

In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage(By similarity). Positive regulator of PARK2 translocation to damaged mitochondria.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
heat shock 70kDa protein 1-like (HSPA1L)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
70 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, IHC, IF, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P34931
Gene ID
3305
Alias
Heat shock 70 kDa protein 1-like (Heat shock 70 kDa protein 1L),Heat shock 70 kDa protein 1-Hom (HSP70-Hom),HSPA1L
Background
Antibody anti-HSPA1L
Status
RUO
Note
Mol. Weight 70 kDa

Descripción

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HSPA1L antibody

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Heat Shock 70 kDa Protein 1-Like (HSPA1L) Antibody

HSPA1L Antibody is a Rabbit Polyclonal antibody against HSPA1L. This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq, Jul 2008].

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