HSPA1L antibody

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Description
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage(By similarity). Positive regulator of PARK2 translocation to damaged mitochondria.
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Product specifications
Category | Primary Antibodies |
Immunogen Target | heat shock 70kDa protein 1-like (HSPA1L) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 70 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, IHC, IF, WB |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | P34931 |
Gene ID | 3305 |
Alias | Heat shock 70 kDa protein 1-like (Heat shock 70 kDa protein 1L),Heat shock 70 kDa protein 1-Hom (HSP70-Hom),HSPA1L |
Background | Antibody anti-HSPA1L |
Status | RUO |
Note | Mol. Weight 70 kDa |
Descripción
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HSPA1L antibody
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage(By similarity). Positive regulator of PARK2 translocation to damaged mitochondria.
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HSPA1L Antibody is a Rabbit Polyclonal antibody against HSPA1L. This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq, Jul 2008].
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