HSD3B7 antibody

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935106861
info@markelab.com
name
HSD3B7 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04032
tested applications
ELISA, WB, IHC

Description

The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis(PubMed:11067870). Plays a key role in cell positioning and movement in lymphoid tissues by mediating degradation of 7-alpha,25-dihydroxycholesterol(7-alpha,25-OHC): 7-alpha,25-OHC acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
hydroxy-delta-5-steroid dehydrogenase, 3 beta-and steroid delta-isomerase 7 (HSD3B7)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
36 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q9H2F3
Gene ID
80270
Alias
3 beta-hydroxysteroid dehydrogenase type 7,3 beta-hydroxysteroid dehydrogenase type VII (3-beta-HSD VII),3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase (C(27) 3-beta-HSD),Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase,HSD3B7
Background
Antibody anti-HSD3B7
Status
RUO
Note
Mol. Weight 36 kDa

Descripción

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