HSD17B6 antibody
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Description
NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity(in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids(in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone(in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone(in vitro). Has retinol dehydrogenase activity towards all-trans-retinol(in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | hydroxysteroid(17-beta) dehydrogenase 6 homolog(Mouse) (HSD17B6) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 33-35kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O14756 |
| Gene ID | 8630 |
| Alias | 17-beta-hydroxysteroid dehydrogenase type 6 (17-beta-HSD 6, 17-beta-HSD6),3-alpha->beta-hydroxysteroid epimerase (3-alpha->beta-HSE),Oxidative 3-alpha hydroxysteroid dehydrogenase,Short chain dehydrogenase/reductase family 9C member 6,HSD17B6,RODH,SDR9C6 |
| Background | Antibody anti-HSD17B6 |
| Status | RUO |
| Note | Mol. Weight 33-35 kDa |
Descripción
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HSD17B6 antibody
NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity(in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids(in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone(in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone(in vitro). Has retinol dehydrogenase activity towards all-trans-retinol(in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.
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