HSD17B11 antibody

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Description
Can convert androstan-3-alpha,17-beta-diol(3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA(dehydroepiandrosterone), or A-dione(4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | hydroxysteroid(17-beta) dehydrogenase 11 (HSD17B11) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 33kd |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q8NBQ5 |
Gene ID | 51170 |
Alias | Estradiol 17-beta-dehydrogenase 11,17-beta-hydroxysteroid dehydrogenase 11 (17-beta-HSD 11, 17bHSD11, 17betaHSD11),17-beta-hydroxysteroid dehydrogenase XI (17-beta-HSD XI, 17betaHSDXI),Cutaneous T-cell lymphoma-associated antigen HD-CL-03 (CTCL-associated antigen HD-CL-03),Dehydrogenase/reductase SDR family member 8,Retinal short-chain dehydrogenase/reductase 2 (retSDR2),Short chain dehydrogenase/reductase family 16C member 2,HSD17B11,DHRS8,PAN1B,SDR16C2 |
Background | Antibody anti-HSD17B11 |
Status | RUO |
Note | Mol. Weight 33 kDa |
Descripción
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HSD17B11 antibody
Can convert androstan-3-alpha,17-beta-diol(3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA(dehydroepiandrosterone), or A-dione(4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.
Ver Producto
HSD17B11 antibody
Can convert androstan-3-alpha,17-beta-diol(3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA(dehydroepiandrosterone), or A-dione(4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.
Ver Producto