HSD17B11 antibody

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935106861
info@markelab.com
name
HSD17B11 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04024
tested applications
ELISA, WB, IHC

Description

Can convert androstan-3-alpha,17-beta-diol(3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA(dehydroepiandrosterone), or A-dione(4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
hydroxysteroid(17-beta) dehydrogenase 11 (HSD17B11)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
33kd
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q8NBQ5
Gene ID
51170
Alias
Estradiol 17-beta-dehydrogenase 11,17-beta-hydroxysteroid dehydrogenase 11 (17-beta-HSD 11, 17bHSD11, 17betaHSD11),17-beta-hydroxysteroid dehydrogenase XI (17-beta-HSD XI, 17betaHSDXI),Cutaneous T-cell lymphoma-associated antigen HD-CL-03 (CTCL-associated antigen HD-CL-03),Dehydrogenase/reductase SDR family member 8,Retinal short-chain dehydrogenase/reductase 2 (retSDR2),Short chain dehydrogenase/reductase family 16C member 2,HSD17B11,DHRS8,PAN1B,SDR16C2
Background
Antibody anti-HSD17B11
Status
RUO
Note
Mol. Weight 33 kDa

Descripción

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