HSPA8 antibody

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935106861
info@markelab.com
name
HSPA8 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab09832
tested applications
ELISA, WB, IHC

Description

HSPA8 (also known as HSC70) is a member of the HSPA (HSP70) family of heat-shock proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSPA8 is a constitutively expressed cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Recently it has been reported that HSPA8 can interact with α-synuclein, the critical pathological protein of Parkinson’s disease, indicating its implication in neurodegenerative disease. (21832061)

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Hsc70 (HSPA8)
Host
Mouse
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:3000-1:20000; IHC: 1:50-1:500
Clonality
monoclonal
Conjugation
Unconjugated
Isotype
IgG1
Clone ID
4E11
Observed MW
70 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Protein A+G purification
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P11142
Gene ID
3312
Alias
Heat shock cognate 71 kDa protein,Heat shock 70 kDa protein 8,Lipopolysaccharide-associated protein 1 (LAP-1, LPS-associated protein 1),HSPA8,HSC70,HSP73,HSPA10
Background
Antibody anti-HSPA8
Status
RUO
Note
Mol. Weight 70 kDa

Descripción

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HSPA8 (also known as HSC70) is a member of the HSPA (HSP70) family of heat-shock proteins which are highly conserved chaperons implicated in protein folding, protein refolding, protein transport, and protein targeting. HSPA8 is a constitutively expressed cytosol/nuclear protein able to translocate between cytoplasm and nucleus. Recently it has been reported that HSPA8 can interact with α-synuclein, the critical pathological protein of Parkinson’s disease, indicating its implication in neurodegenerative disease. (21832061)

Ver Producto