Histone H3.3 antibody

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Documents del producto
Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | H3 histone, family 3A (Histone H3.3)  | 
| Host | Rabbit  | 
| Reactivity | Human, Mouse, Rat  | 
| Recommended Dilution | WB: 1:500-1:1000; IHC: 1:50-1:500  | 
| Clonality | polyclonal  | 
| Conjugation | Unconjugated  | 
| Isotype | IgG  | 
| Observed MW | 15-17 kDa  | 
| Purity | ≥95% as determined by SDS-PAGE  | 
| Purification | Immunogen affinity purified  | 
| Size 1 | 100µg  | 
| Form | liquid  | 
| Tested Applications | ELISA, WB, IHC  | 
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)  | 
| UniProt ID | P84243  | 
| Alias | Histone H3.3,H3-3A,H3.3A,H3F3,H3F3A  | 
| Background | Antibody anti-Histone H3.3  | 
| Status | RUO  | 
| Note | Mol. Weight 15-17 kDa  | 
Related Products

Histone H3.3 antibody
Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Ver Producto
Histone H3.3 antibody
Ver Producto
Histone H3.3 (pS32) Antibody
Histone H3.3 (pS32) Antibody is a Rabbit Polyclonal Antibody against Histone H3.3 (pS32).
Ver Producto