anti- HER2/ErbB2 antibody

Name: anti- HER2/ErbB2 antibody
Brand: FineTest
SKU: FNab03834
Availability: OnlineOnly

Pida mas información

935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-HER2/ErbB2

proveedor

FineTest

reference

FNab03834

Tested Applications

ELISA, WB, IHC, IF

reactivity

human

status

RUO

clonality

polyclonal

Descripción

This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors.

Características del producto

clonality

polyclonal

reactivity

human

immunogen target

v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog(avian)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, IHC, IF

observerd MW

185 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

HER2/ErbB2

alias

CD340, ERBB2, HER 2, HER 2/neu, HER2, MLN 19, MLN19, NEU, NGL, p185, p185erbB2, Proto oncogene c ErbB 2, Proto oncogene Neu, TKR1

uniprot id

https://www.uniprot.org/uniprotkb/P04626

gene id

https://www.ncbi.nlm.nih.gov/gene/2064

note

This product is for research use only.

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