GTPBP4 antibody
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Description
Involved in the biogenesis of the 60S ribosomal subunit.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | GTP binding protein 4 (GTPBP4) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 74 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9BZE4 |
| Gene ID | 23560 |
| Alias | GTP-binding protein 4,Chronic renal failure gene protein,GTP-binding protein NGB,Nucleolar GTP-binding protein 1,GTPBP4,CRFG,NOG1 |
| Background | Antibody anti-GTPBP4 |
| Status | RUO |
| Note | Mol. Weight 74 kDa |
Descripción
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Recombinant Human GTPBP4
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GTP Binding Protein 4 (GTPBP4) Antibody
GTPBP4 Antibody is a Rabbit Polyclonal antibody against GTPBP4. GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.
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