GSPT2 antibody
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935106861
info@markelab.com
name
GSPT2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03681
tested applications
ELISA, WB, IHC
Description
Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome-and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay(NMD) of mRNAs containing premature stop codons.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | G1 to S phase transition 2 (GSPT2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 69 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8IYD1 |
| Gene ID | 23708 |
| Alias | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (Eukaryotic peptide chain release factor subunit 3b, eRF3b),G1 to S phase transition protein 2 homolog,GSPT2,ERF3B |
| Background | Antibody anti-GSPT2 |
| Status | RUO |
| Note | Mol. Weight 69 kDa |
Descripción
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