GSPT1 antibody

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935106861
info@markelab.com
name
GSPT1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03680
tested applications
ELISA, WB, IHC
Description
Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay(NMD) of mRNAs containing premature stop codons.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | G1 to S phase transition 1 (GSPT1) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 80 kDa ; 84 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | P15170 |
Gene ID | 2935 |
Alias | Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a, eRF3a),G1 to S phase transition protein 1 homolog,GSPT1,ERF3A |
Background | Antibody anti-GSPT1 |
Status | RUO |
Note | Mol. Weight 80 kDa;84 kDa |
Descripción
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GSPT1 antibody
Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the activity of ERF1. Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay(NMD) of mRNAs containing premature stop codons.
Ver Producto