HSPA9 antibody
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Description
GRP75(also known as mortalin, HSPA9 or mt-Hsp70) is a constitutively expressed member of the HSPA(HSP70) family of heat-shock proteins. It is located in the mitochondrial matrix and anti-GRP75 is commonly used as the marker for mitochondria. It has been reported that GRP75 is enriched in cancer cells and contributes to carcinogenesis. In addition, decreased expression level of GRP75 has been found in neurodegenerative disorders like Parkinson’s disease.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | heat shock 70kDa protein 9(mortalin) (HSPA9) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:1000-1:4000; IP: 1:1000-1:4000; IHC: 1:20-1:200; IF: 1:10-1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 74 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, FC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P38646 |
| Alias | Stress-70 protein, mitochondrial,75 kDa glucose-regulated protein (GRP-75),Heat shock 70 kDa protein 9,Mortalin (MOT),Peptide-binding protein 74 (PBP74),HSPA9,GRP75,HSPA9B,mt-HSP70 |
| Background | Antibody anti-HSPA9 |
| Status | RUO |
| Note | Mol. Weight 74 kDa |
Descripción
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HSPA9 antibody
GRP75(also known as mortalin, HSPA9 or mt-Hsp70) is a constitutively expressed member of the HSPA(HSP70) family of heat-shock proteins. It is located in the mitochondrial matrix and anti-GRP75 is commonly used as the marker for mitochondria. It has been reported that GRP75 is enriched in cancer cells and contributes to carcinogenesis. In addition, decreased expression level of GRP75 has been found in neurodegenerative disorders like Parkinson’s disease.
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