GRK1 antibody
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Description
Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin(RHO), the G protein-coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | G protein-coupled receptor kinase 1 (GRK1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 64 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q15835 |
| Gene ID | 6011 |
| Alias | Rhodopsin kinase GRK1 (RK),G protein-coupled receptor kinase 1,GRK1,RHOK |
| Background | Antibody anti-GRK1 |
| Status | RUO |
| Note | Mol. Weight 64 kDa |
Descripción
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GRK1 antibody
Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin(RHO), the G protein-coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.
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Rhodopsin Kinase (GRK1) Antibody
GRK1 Antibody is a Rabbit Polyclonal antibody against GRK1. This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.
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Rhodopsin Kinase (GRK1) Antibody
GRK1 Antibody is a Rabbit Polyclonal antibody against GRK1. This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2).
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