GPT antibody
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935106861
info@markelab.com
name
GPT antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03619
tested applications
ELISA, WB, IHC
Description
This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | glutamic-pyruvate transaminase (alanine aminotransferase) (GPT) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200 - 1:1000; IHC: 1:50 - 1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 50 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P24298 |
| Gene ID | 2875 |
| Alias | Alanine aminotransferase 1 (ALT1),Glutamate pyruvate transaminase 1 (GPT 1),Glutamic--alanine transaminase 1,Glutamic--pyruvic transaminase 1,GPT,AAT1,GPT1 |
| Background | Antibody anti-GPT |
| Status | RUO |
| Note | Mol. Weight 50 kDa |
Descripción
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GPT antibody
This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.
Ver Producto