GNAO1 antibody

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
The protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G-protein signal-transducing complex. Defects in this gene are a cause of early-onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O (GNAO1) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 39 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, IHC, WB |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
UniProt ID | P09471 |
Gene ID | 2775 |
Alias | Guanine nucleotide-binding protein G(o) subunit alpha,GNAO1 |
Background | Antibody anti-GNAO1 |
Status | RUO |
Note | Mol. Weight 39 kDa |
Descripción
Related Products

Human GNAO1 (Guanine nucleotide-binding protein G (o) subunit alpha) ELISA Kit
Ver Producto
GNAO1 antibody
The protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G-protein signal-transducing complex. Defects in this gene are a cause of early-onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene.
Ver Producto
Guanine Nucleotide Binding Protein (G Protein), Alpha Activating Activity Polypeptide O (GNAO1) Antibody
GNAO1 Antibody is a Rabbit Polyclonal antibody against GNAO1. Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of second messenger signalling cascades. There are several types of Galpha proteins; Galphas and Galphai bind directly to adenylyl cyclase and stimulate or inhibit its activity, leading to an increase or decrease in cAMP levels respectively.
Ver Producto