GNAO1 antibody

Product Graph
Contáctenos para saber el precio

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
GNAO1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03534
tested applications
ELISA, IHC, WB

Description

The protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G-protein signal-transducing complex. Defects in this gene are a cause of early-onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene.

Documents del producto

Instrucciones
Descargar
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O (GNAO1)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
39 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, IHC, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
UniProt ID
P09471
Gene ID
2775
Alias
Guanine nucleotide-binding protein G(o) subunit alpha,GNAO1
Background
Antibody anti-GNAO1
Status
RUO
Note
Mol. Weight 39 kDa

Descripción

Related Products

EH8843

Human GNAO1 (Guanine nucleotide-binding protein G (o) subunit alpha) ELISA Kit

Ver Producto
FNab03534

GNAO1 antibody

The protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G-protein signal-transducing complex. Defects in this gene are a cause of early-onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene.

Ver Producto
abx001952

Guanine Nucleotide Binding Protein (G Protein), Alpha Activating Activity Polypeptide O (GNAO1) Antibody

GNAO1 Antibody is a Rabbit Polyclonal antibody against GNAO1. Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of second messenger signalling cascades. There are several types of Galpha proteins; Galphas and Galphai bind directly to adenylyl cyclase and stimulate or inhibit its activity, leading to an increase or decrease in cAMP levels respectively.

Ver Producto