GH2 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
GH2 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab03448
Tested Applications
ELISA, WB, IHC
Description
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | growth hormone 2 (GH2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 23-25kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P01242 |
| Gene ID | 2689 |
| Alias | GHL,GHV,GH-V,GHB2,hGH-V,Growth hormone variant,Placenta-specific growth hormone |
| Background | Antibody anti-GH2 |
| Status | RUO |
| Note | Mol. Weight 23-25 kDa |
Background
Growth hormone 2 (GH2) is a member of the growth hormone gene family primarily expressed in the placenta, where it plays a critical role in regulating fetal growth and maternal metabolic adaptations during pregnancy GH2 is structurally similar to growth hormone 1 (GH1) but has distinct roles in enhancing placental development and nutrient transport to the fetus It stimulates insulin-like growth factor 1 (IGF-1) production and modulates maternal glucose and lipid metabolism to ensure fetal nutrient supply Dysregulation of GH2 expression has been associated with placental insufficiency, intrauterine growth restriction (IUGR), and gestational diabetes GH2 also influences immune responses during pregnancy, promoting tolerance to the fetus while maintaining maternal immunity Emerging studies suggest that alterations in GH2 expression may contribute to pregnancy complications and metabolic disorders, highlighting its importance in fetal development and maternal physiology
Productos relacionados
Growth Hormone Variant (GH2) Antibody
Growth Hormone 2 Antibody is a Rabbit Polyclonal antibody against Growth Hormone 2.…
Ver producto
Growth Hormone Variant (GH2) Antibody
Growth Hormone 2 Antibody is a Rabbit Polyclonal against Growth Hormone 2.…
Ver producto
Human Growth Hormone Variant (GH2) ELISA Kit
Human Growth Hormone Variant (GH2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Growth H…
Ver producto