GGT7 antibody

Este producto es parte de GGT - Gamma-Glutamyltransferase
GGT7 antibody
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Name
GGT7 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab03447
Tested Applications
ELISA, IHC, WB

Description

Cleaves glutathione conjugates.

Documentos del producto

Instrucciones
Descargar
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
gamma-glutamyltransferase 7 (GGT7)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
75-100 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, IHC, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q9UJ14
Gene ID
2686
Alias
GGT4,GGTL3,GGTL5,D20S101,Gamma-glutamyltransferase like 5,Gamma-glutamyltransferase like 5,Glutathione hydrolase 7
Background
Antibody anti-GGT7
Status
RUO
Note
Mol. Weight 75-100 kDa

Background

Gamma-glutamyltransferase 7 (GGT7) is another member of the gamma-glutamyltransferase enzyme family involved in the breakdown and recycling of glutathione, a critical molecule for antioxidant defense and detoxification pathways GGT7 is expressed in tissues such as the kidney, liver, and lungs, where it regulates the metabolism of gamma-glutamyl compounds, supporting amino acid transport and redox homeostasis Dysregulation of GGT7 activity has been associated with metabolic disorders, cardiovascular diseases, and cancers, where it contributes to oxidative stress and inflammation GGT7 is particularly relevant in tumor biology, where its role in glutathione metabolism supports cellular survival under oxidative stress conditions Elevated GGT7 expression has been linked to drug resistance in cancer cells by enhancing detoxification pathways Its emerging role in immune regulation and cellular stress responses highlights its importance in maintaining homeostasis under physiological and pathological conditions

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