PIP antibody

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935106861
info@markelab.com
name
PIP antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03381
tested applications
ELISA, IHC

Description

GCDFP-15(gross cystic disease fluid protein 15), also known as PIP(prolactin-induced protein) is a secretory glycoprotein expressed in benign and malignant breast tumor tissues and in some normal exocrine organs such as sweat, salivary, and lacrimal glands(PMID: 12393800). GCDFP-15 expression is increased by prolactin and androgen and inhibited by estrogen(PMID: 18854942). The expression is also regulated by interleukins. GCDFP-15 is a marker of apocrine differentiation and is frequently used for assessment of metastases or regional recurrences of breast origin.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
prolactin-induced protein (PIP)
Host
Rabbit
Reactivity
Human
Recommended Dilution
IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P12273
Alias
Prolactin-inducible protein,Gross cystic disease fluid protein 15 (GCDFP-15),Prolactin-induced protein,Secretory actin-binding protein (SABP),gp17,PIP,GCDFP15,GPIP4
Background
Antibody anti-PIP
Status
RUO
Note
This product is for research use only.

Descripción

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GCDFP-15(gross cystic disease fluid protein 15), also known as PIP(prolactin-induced protein) is a secretory glycoprotein expressed in benign and malignant breast tumor tissues and in some normal exocrine organs such as sweat, salivary, and lacrimal glands(PMID: 12393800). GCDFP-15 expression is increased by prolactin and androgen and inhibited by estrogen(PMID: 18854942). The expression is also regulated by interleukins. GCDFP-15 is a marker of apocrine differentiation and is frequently used for assessment of metastases or regional recurrences of breast origin.

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