GBP5 antibody
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935106861
info@markelab.com
name
GBP5 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03376
tested applications
ELISA, IHC, IF, WB, FC
Description
As an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents(PubMed:22461501). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP(PubMed:20180847).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | guanylate binding protein 5 (GBP5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 65 kDa, 55 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, IF, WB, FC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q96PP8 |
| Gene ID | 115362 |
| Alias | Guanylate-binding protein 5,GBP-TA antigen,GTP-binding protein 5 (GBP-5),Guanine nucleotide-binding protein 5,GBP5 |
| Background | Antibody anti-GBP5 |
| Status | RUO |
| Note | Mol. Weight 65 kDa, 55 kDa |
Descripción
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GBP5 antibody
As an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents(PubMed:22461501). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP(PubMed:20180847).
Ver Producto