GATA1 antibody

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Description
Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS(PubMed:24245781).
Documents del producto
Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | GATA binding protein 1(globin transcription factor 1) (GATA1)  | 
| Host | Rabbit  | 
| Reactivity | Human, Mouse, Rat  | 
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200  | 
| Clonality | polyclonal  | 
| Conjugation | Unconjugated  | 
| Isotype | IgG  | 
| Observed MW | 55 kDa  | 
| Purity | ≥95% as determined by SDS-PAGE  | 
| Purification | Immunogen affinity purified  | 
| Size 1 | 100µg  | 
| Form | liquid  | 
| Tested Applications | ELISA, WB, IHC  | 
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)  | 
| UniProt ID | P15976  | 
| Gene ID | 2623  | 
| Alias | Erythroid transcription factor,Eryf1,GATA-binding factor 1 (GATA-1, GF-1),NF-E1 DNA-binding protein,GATA1,ERYF1,GF1  | 
| Background | Antibody anti-GATA1  | 
| Status | RUO  | 
| Note | Mol. Weight 55 kDa  | 
Descripción
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GATA1 antibody
Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS(PubMed:24245781).
Ver Producto
GATA1 antibody
Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS(PubMed:24245781).
Ver Producto