anti- GAMT antibody
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Description
Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor(PubMed:26003046, PubMed:24415674, PubMed:26319512). Important in nervous system development(PubMed:24415674).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | guanidinoacetate N-methyltransferase |
| Host | Rabbit |
| Reactivity | human,mouse,rat,zebrafish |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 26 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q14353 |
| Gene ID | 8139 |
| Background | Antibody anti-GAMT |
| Status | RUO |
| Note | This product is for research use only. |
Descripción
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anti- GAMT antibody
Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor(PubMed:26003046, PubMed:24415674, PubMed:26319512). Important in nervous system development(PubMed:24415674).
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GAMT Antibody is a Rabbit Polyclonal antibody against GAMT. The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.
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