G3BP1 antibody

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935106861
info@markelab.com
name
G3BP1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03267
tested applications
ELISA, WB, IP, IF, IHC, FC
Description
May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP-and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'-and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.
Documents del producto
Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | GTPase activating protein(SH3 domain) binding protein 1 (G3BP1)  | 
| Host | Rabbit  | 
| Reactivity | Human, Mouse, Rat  | 
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200  | 
| Clonality | polyclonal  | 
| Conjugation | Unconjugated  | 
| Isotype | IgG  | 
| Observed MW | 55-60 kDa  | 
| Purity | ≥95% as determined by SDS-PAGE  | 
| Purification | Immunogen affinity purified  | 
| Size 1 | 100µg  | 
| Form | liquid  | 
| Tested Applications | ELISA, WB, IP, IF, IHC, FC  | 
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)  | 
| UniProt ID | Q13283  | 
| Gene ID | 10146  | 
| Alias | Ras GTPase-activating protein-binding protein 1 (G3BP-1),ATP-dependent DNA helicase VIII (hDH VIII),GAP SH3 domain-binding protein 1,G3BP1,G3BP  | 
| Background | Antibody anti-G3BP1  | 
| Status | RUO  | 
| Note | Mol. Weight 55-60 kDa  | 
Descripción
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May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP-and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'-and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.
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