anti- FRS2 antibody

Descripción

Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

Características del producto

clonality

polyclonal

reactivity

human,mouse,rat

immunogen target

fibroblast growth factor receptor substrate 2

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, IHC, WB, IF

observerd MW

60 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

FRS2

alias

FRS2A, FRS2alpha, SNT, SNT-1, SNT1, FRS1A,FGFR substrate 2,FGFR-signaling adaptor SNT

uniprot id

https://www.uniprot.org/uniprotkb/Q8WU20

gene id

https://www.ncbi.nlm.nih.gov/gene/10818

note

This product is for research use only.

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