FRK antibody

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935106861
info@markelab.com
name
FRK antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03224
tested applications
ELISA, WB, IHC, IF
Description
Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | fyn-related kinase (FRK) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 54-57 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P42685 |
| Gene ID | 2444 |
| Alias | Tyrosine-protein kinase FRK,FYN-related kinase,Nuclear tyrosine protein kinase RAK,Protein-tyrosine kinase 5,FRK,PTK5,RAK |
| Background | Antibody anti-FRK |
| Status | RUO |
| Note | Mol. Weight 54-57 kDa |
Descripción
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