FIS1 antibody
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935106861
info@markelab.com
name
FIS1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03132
tested applications
ELISA, IHC, IF, IP, WB
Description
Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1(DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | fission 1(mitochondrial outer membrane) homolog (FIS1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:1000-1:3000; IHC: 1:10-1:100; IF: 1:50-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 17 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, IF, IP, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9Y3D6 |
| Gene ID | 51024 |
| Alias | Mitochondrial fission 1 protein,FIS1 homolog (hFis1),Tetratricopeptide repeat protein 11 (TPR repeat protein 11),FIS1,TTC11 |
| Background | Antibody anti-FIS1 |
| Status | RUO |
| Note | Mol. Weight 17 kDa |
Descripción
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FIS1 antibody
Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1(DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
Ver Producto