FBXO7 antibody
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935106861
info@markelab.com
name
FBXO7 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03049
tested applications
ELISA, WB, IHC, IP
Description
Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy(mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | F-box protein 7 (FBXO7) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 58.5 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9Y3I1 |
| Gene ID | 25793 |
| Alias | F-box only protein 7,FBXO7,FBX7 |
| Background | Antibody anti-FBXO7 |
| Status | RUO |
| Note | Mol. Weight 58.5 kDa |
Descripción
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