FBXL15 antibody

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Description
Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | F-box and leucine-rich repeat protein 15 (FBXL15) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 33 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9H469 |
| Gene ID | 79176 |
| Alias | F-box/LRR-repeat protein 15,F-box only protein 37,FBXL15,FBXO37 |
| Background | Antibody anti-FBXL15 |
| Status | RUO |
| Note | Mol. Weight 33 kDa |
Descripción
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