FBP1 antibody

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935106861
info@markelab.com
name
FBP1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab10418
tested applications
ELISA, WB

Description

Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
fructose-1,6-bisphosphatase 1 (FBP1)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
37 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P09467
Gene ID
2203
Alias
Fructose-1,6-bisphosphatase 1 (FBPase 1),D-fructose-1,6-bisphosphate 1-phosphohydrolase 1,Liver FBPase,FBP1,FBP
Background
Antibody anti-FBP1
Status
RUO
Note
Mol. Weight 37 kDa

Descripción

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