FBLIM1 antibody
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935106861
info@markelab.com
name
FBLIM1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab03028
tested applications
ELISA, WB, IHC
Description
Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation(spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | filamin binding LIM protein 1 (FBLIM1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 45-48 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8WUP2 |
| Gene ID | 54751 |
| Alias | Filamin-binding LIM protein 1 (FBLP-1),Migfilin,Mitogen-inducible 2-interacting protein (MIG2-interacting protein),FBLIM1,FBLP1 |
| Background | Antibody anti-FBLIM1 |
| Status | RUO |
| Note | Mol. Weight 45-48 kDa |
Descripción
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