FAF2 antibody
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935106861
info@markelab.com
name
FAF2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02947
tested applications
ELISA, WB, IHC, IP, IF
Description
Plays an important role in endoplasmic reticulum-associated degradation(ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins(PubMed:18711132, PubMed:24215460). Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis(PubMed:23297223).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Fas associated factor family member 2 (FAF2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 53 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q96CS3 |
| Gene ID | 23197 |
| Alias | FAS-associated factor 2,UBX domain-containing protein 3B,UBX domain-containing protein 8,FAF2,ETEA,KIAA0887,UBXD8,UBXN3B |
| Background | Antibody anti-FAF2 |
| Status | RUO |
| Note | Mol. Weight 53 kDa |
Descripción
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FAF2 antibody
Plays an important role in endoplasmic reticulum-associated degradation(ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins(PubMed:18711132, PubMed:24215460). Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis(PubMed:23297223).
Ver Producto