ESX1 antibody
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935106861
info@markelab.com
name
ESX1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02873
tested applications
ELISA, WB, IP
Description
May coordinately regulate cell cycle progression and transcription during spermatogenesis. Inhibits degradation of polyubiquitinated cyclin A and cyclin B1 and thereby arrests the cell cycle at early M phase. ESXR1-N acts as a transcriptional repressor. Binds to the sequence 5'-TAATGTTATTA-3' which is present within the first intron of the KRAS gene and inhibits its expression. ESXR1-C has the ability to inhibit cyclin turnover.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ESX homeobox 1 (ESX1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 65 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8N693 |
| Gene ID | 80712 |
| Alias | Homeobox protein ESX1,Extraembryonic, spermatogenesis, homeobox 1,Homeobox protein ESX1-N,Homeobox protein ESX1-C,ESX1,ESX1L,ESX1R |
| Background | Antibody anti-ESX1 |
| Status | RUO |
| Note | Mol. Weight 65 kDa |
Descripción
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