ESRP2 antibody

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935106861
info@markelab.com
name
ESRP2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02870
tested applications
ELISA, WB
Description
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition(EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | epithelial splicing regulatory protein 2 (ESRP2) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 78 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9H6T0 |
| Gene ID | 80004 |
| Alias | Epithelial splicing regulatory protein 2,RNA-binding motif protein 35B,RNA-binding protein 35B,ESRP2,RBM35B |
| Background | Antibody anti-ESRP2 |
| Status | RUO |
| Note | Mol. Weight 78 kDa |
Descripción
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