ESRP2 antibody

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935106861
info@markelab.com
name
ESRP2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02870
tested applications
ELISA, WB

Description

mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition(EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
epithelial splicing regulatory protein 2 (ESRP2)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
78 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q9H6T0
Gene ID
80004
Alias
Epithelial splicing regulatory protein 2,RNA-binding motif protein 35B,RNA-binding protein 35B,ESRP2,RBM35B
Background
Antibody anti-ESRP2
Status
RUO
Note
Mol. Weight 78 kDa

Descripción

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