ERLIN1 antibody

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935106861
info@markelab.com
name
ERLIN1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02848
tested applications
ELISA, WB, IHC, IP, IF
Description
Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation(ERAD) of inositol 1,4,5-trisphosphate receptors(IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex(PubMed:24217618).
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | ER lipid raft associated 1 (ERLIN1) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 39 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, IP, IF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | O75477 |
Gene ID | 10613 |
Alias | Erlin-1,Endoplasmic reticulum lipid raft-associated protein 1,Protein KE04,Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1 (SPFH domain-containing protein 1),ERLIN1,C10orf69,KE04,KEO4,SPFH1 |
Background | Antibody anti-ERLIN1 |
Status | RUO |
Note | Mol. Weight 39 kDa |
Descripción
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