ERLIN1 antibody

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935106861
info@markelab.com
name
ERLIN1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02848
tested applications
ELISA, WB, IHC, IP, IF

Description

Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation(ERAD) of inositol 1,4,5-trisphosphate receptors(IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex(PubMed:24217618).

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
ER lipid raft associated 1 (ERLIN1)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
39 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IP, IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
O75477
Gene ID
10613
Alias
Erlin-1,Endoplasmic reticulum lipid raft-associated protein 1,Protein KE04,Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1 (SPFH domain-containing protein 1),ERLIN1,C10orf69,KE04,KEO4,SPFH1
Background
Antibody anti-ERLIN1
Status
RUO
Note
Mol. Weight 39 kDa

Descripción

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