ERCC6 antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex(DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | excision repair cross-complementing rodent repair deficiency, complementation group 6 (ERCC6) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 150kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q03468 |
| Gene ID | 2074 |
| Alias | DNA excision repair protein ERCC-6,ATP-dependent helicase ERCC6,Cockayne syndrome protein CSB,ERCC6,CSB |
| Background | Antibody anti-ERCC6 |
| Status | RUO |
| Note | Mol. Weight 150 kDa |
Descripción
Related Products
ERCC6 antibody
Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex(DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.
Ver ProductoERCC6 antibody
Essential factor involved in transcription-coupled nucleotide excision repair which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation. It recruits the CSA complex(DCX(ERCC8) complex), nucleotide excision repair proteins and EP300 to the at sites of RNA polymerase II-blocking lesions.
Ver Producto
Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation 6 (ERCC6) Antibody
Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 Antibody is a Rabbit Polyclonal antibody against Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6.
Ver Producto