ELOVL6 antibody
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Description
Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long-and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ELOVL family member 6, elongation of long chain fatty acids(FEN1/Elo2, SUR4/Elo3-like, yeast) (ELOVL6) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 45kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9H5J4 |
| Gene ID | 79071 |
| Alias | Very long chain fatty acid elongase 6,3-keto acyl-CoA synthase ELOVL6,ELOVL fatty acid elongase 6 (ELOVL FA elongase 6),Elongation of very long chain fatty acids protein 6,Fatty acid elongase 2 (hELO2),Fatty acyl-CoA elongase,Long-chain fatty-acyl elongase,Very long chain 3-ketoacyl-CoA synthase 6,Very long chain 3-oxoacyl-CoA synthase 6,ELOVL6,FACE,LCE |
| Background | Antibody anti-ELOVL6 |
| Status | RUO |
| Note | Mol. Weight 45 kDa |
Descripción
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