EIF4G1 antibody
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Description
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | eukaryotic translation initiation factor 4 gamma, 1 (EIF4G1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 230 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q04637 |
| Gene ID | 1981 |
| Alias | Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1, eIF-4G 1, eIF-4G1),p220,EIF4G1,EIF4F,EIF4G,EIF4GI |
| Background | Antibody anti-EIF4G1 |
| Status | RUO |
| Note | Mol. Weight 230 kDa |
Descripción
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