EIF3I antibody
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935106861
info@markelab.com
name
EIF3I antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02710
tested applications
ELISA, IHC, IF, IP, WB, FC
Description
Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | eukaryotic translation initiation factor 3, subunit I (EIF3I) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 36kd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, IF, IP, WB, FC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q13347 |
| Gene ID | 8668 |
| Alias | Eukaryotic translation initiation factor 3 subunit I (eIF3i),Eukaryotic translation initiation factor 3 subunit 2,TGF-beta receptor-interacting protein 1 (TRIP-1),eIF-3-beta,eIF3 p36,EIF3I,EIF3S2,TRIP1 |
| Background | Antibody anti-EIF3I |
| Status | RUO |
| Note | Mol. Weight 36 kDa |
Descripción
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Human EIF3I (Eukaryotic translation initiation factor 3 subunit I) ELISA Kit
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EIF3I antibody
Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Ver Producto