EEF2K antibody

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935106861
info@markelab.com
name
EEF2K antibody
category
Primary Antibodies
provider
FineTest
reference
FNab02652
tested applications
ELISA, WB

Description

Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
eukaryotic elongation factor-2 kinase (EEF2K)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
100 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
O00418
Gene ID
29904
Alias
Eukaryotic elongation factor 2 kinase (eEF-2 kinase, eEF-2K),Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase,EEF2K
Background
Antibody anti-EEF2K
Status
RUO
Note
Mol. Weight 100 kDa

Descripción

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Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced.

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